Chromatin condensation, diagram
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Chromatin condensation, diagram
Chromatin condensation, diagram. This sequence, from right to left, shows the stages by which a long strand of DNA (deoxyribonucleic acid, far right) is combined with various proteins to form chromatin, and is then coiled and compacted to form a chromosome (far left). The intermediate stages include histone cores (blue, centre right) that form beads on a string and fibre structures. Further scaffold proteins help coil the fibre (centre left). This compaction process is required to fit DNA strands (typically 2 metres in length) inside cell nuclei (less than 0.1 millimetres across). The scale in nanometres (nm) is across top
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Media ID 6327825
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Chromatin Chromosome Coil Coiling Compact Compacting Comparison Condensing Diagram Euchromatin Fibre Genetic Heterochromatin Histone Histones Molecular Biology Nucleosome Promoter Proteins Scale Series Size Sizes Structural Bio Chemistry Biochemical Condense Deoxyribonucleic Acid Genetics Molecular
EDITORS COMMENTS
This print showcases the intricate process of chromatin condensation, a fundamental mechanism in molecular biology. The diagram takes us on a visual journey from right to left, unveiling the stages through which DNA transforms into chromosomes. Starting at the far right, we witness a long strand of DNA composed of deoxyribonucleic acid. As this genetic material interacts with various proteins, it forms chromatin and undergoes coiling and compaction. The intermediate stages reveal histone cores represented by blue beads on a string and fiber structures. To further facilitate compaction, scaffold proteins come into play as they coil the fiber towards the center-left region of the diagram. This entire process is crucial for accommodating DNA strands that can stretch up to 2 meters in length within cell nuclei measuring less than 0.1 millimeters across. The scale displayed across the top provides an indication of size in nanometers (nm), emphasizing just how compact these structures become during condensation. This illustration not only highlights the structural complexity involved but also emphasizes its significance in genetics and molecular biology. It sheds light on key elements such as nucleosomes, euchromatin, heterochromatin, epigenetic modifications like histone tails, and even enzymes like HDAC that regulate gene expression. Overall, this artwork from Science Photo Library offers an insightful glimpse into one of nature's most fascinating processes – chromatin condensation – showcasing both its beauty and scientific importance.
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